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Analyzing cannabis flowers according to the German Pharmacopeia - monograph 2018

Application No.: VPH0072

Analyzing cannabis flowers according to the German Pharmacopeia - monograph 2018

Since the change in German narcotics law in 2017 (§1 Abs. 1, Betäubungsmittelgesetz; BtMG) the need for reliable and robust HPLC methods for quality control has drastically increased. Six common cannabinoids of high medicinal interest Cannabidiol (CBD), Cannabidiolic acid (CBDA), Cannabinol (CBN), Δ8-Tetrahydrocannabinol (Δ8-THC), Δ9-Tetrahydrocannabinol (Δ9-THC) and Δ9-Tetrahydrocannabinolic acid (Δ9-THCA) were quantified on the KNAUER AZURA® HPLC plus system according to the monograph of German Pharmacopeia 2018 (Deutsches Arzneibuch; DAB). The method was verified using an authorized medicinal cannabis flower available on the market. The assignment of the analytes was made with chemical reference standards.

Technical Data

Application details

Method HPLC
Mode RP
Substances CBD, CBDA, CBN, Δ9-THC, Δ8-THC, Δ9-THCA
Key words bediol, DAB, CBD, CBDA CBN, Δ9-THC, Δ8-THC, Δ9THCA, cannabis, german pharmacopeia, cannabinoids, cannabis flowers, cannabis sativa L.
CAS number 13956-29-1, 1244-58-2, 521-35-7, 5957-75-5, 1972-08-3, 23978-85-0

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