Let your application define your system solution.

In HPLC, components of a mixture are carried through the stationary phase by the flow of a mobile phase and separation is based on differences in migration rates among the sample components. Therefore, the nature of your analytes defines not only the method but also the HPLC system.

Main characteristics of the analytes:

MOLECULAR WEIGHT defines the pore size of the stationary phase

SOLUBILITY defines the HPLC mode, chemistry of stationary phase and eluent.

CONCENTRATION AND MATRIX define the detection parameters and column dimensions.

The solubility of your analytes defines the HPLC mode. The elutropic series defines the solvent strength for the most often used chromatography modes normal phase and reversed phase.

Analytical HPLC/UHPLC system

Efficient and adaptable to your needs

Flow chart of an analytical HPLC system

The analytical HPLC and UHPLC systems of the KNAUER AZURA liquid chromatography instruments are designed to support and facilitate your work. Whether doing routine analysis or demanding separation tasks, AZURA systems are the right tool to overcome your analytical challenges. Choose between different gradient forming technologies and maximum flow rates to find the best configuration for your task.

AZURA® Analytical HPLC systems

More Analytical HPLC systems


  • Mobile Control
  • OpenLAB® CDS EZChrom Edition
  • ClarityChrom® CDS
  • Chromeleon™ 7.2
  • Mobile Control

    The Mobile Control is an intuitive and cost-effective software solution for controlling and monitoring your AZURA devices and systems. The clear system overview provides instant information on key parameters and system status. Adjust and operate single devices or even whole systems with a few fingertips. The well-structured block programming assists you to clearly and quickly automate device control. A smart user management makes the Mobile Control safe. Device parameters can only be changed by authorized operators. 

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  • OpenLAB® CDS EZChrom Edition

    Basic Workstation license, includes System Suitability, Fraction Collector Control and Software Maintenance Agreement

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  • ClarityChrom® CDS

    ClarityChrom is an easy-to-use chromatography data system for workstations. The optional control extensions for GC, PDA and GPC allow to use the software for a wide range of applications.

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  • Chromeleon™ 7.2

    Thermo Scientific™ Dionex™ Chromeleon™ is one of the most wide-spread chromatography data systems. Its intuitive handling benefits laboratory workflow and the highly developed algorithms simplify data processing. It offers a broad range of third-party drivers and can be easily used with existing HPLC systems. KNAUER offers drivers for a lot of its devices. 

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Configure your perfect (U) HPLC system

Build a custom solution based on your requirements. Choose the system components you need. We create an individual system for you. Chromatography by KNAUER!

HPLC Basics –
Principles and parameters

Liquid chromatography is a well-established technique for the separation of substances. High performance liquid chromatography (HPLC) is a suitable method for the analysis of a wide range of application areas. Here, we describe the principle of HPLC and introduce to the most important components in an HPLC system and the factors that determine the success of a measurement.

Application areas


Discover the wide range of possible applications.

View the complete AZURA analytical brochure

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