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Zwitterionic and polar columns for HILIC applications
Zwitterionic HILIC phases are ideal for the analysis of polar and ionizable compounds.
Zwitterionic HILIC phases are ideal for the analysis of polar and ionizable compounds.
Based on ultra-pure Silica gel zwitterionic HILIC phases are ideal for the analysis of polar and ionizable compounds. Stronger interaction of more polar compounds with stationary aqueous layer
Faster elution of nonpolar compounds is possible due to minor hydrophobic interactions. Retention increases with the charge of the analyte.
Recommended for the analysis of hydrophilic compounds like:
Ultra pure, spherical high performance HPLC phase based on silica gel. Zwitterionic modification: Ammonium – sulfonic acid, 7 % carbon content
Separation mechanism: Hydrophilic and weak electrostatic interactions
Modern HILIC phase with zwitterionic modification on the basis of ammonium- sulfonic acid outstanding mechanical and chemical stability
HILIC phase based on ultra-pure silica gel (purity > 99 %), metal content < 10 ppm, pH-stability 2 - 8, pore size 100 A, particle size 3 μm and 5 μm