The C18A modification is more polar compared to a classical C18 phase and can also be used with 100% aqueous eluents. Therewith, it is more often used for the analysis of hydrophilic proteins.
Ultra pure, spherical wide pore HPLC phase based on silica gel
Unpolar, monomeric C18 (Octadecyl) modification, endcapped, with 7 % carbon content (hydrophilic endcapping).
Separation mechanism: Hydrophobic interaction
Eurosil Bioselect 300 C18A has been specifically developed for the determination and purification of peptides, proteins, and oligonucleotides up to MW approx. 5,000 Da. The optimized manufacturing process guarantees excellent batch–to-batch reproducibility. The Eurosil Bioselect sorbent is the first choice for Biochromatography with silica material.
C18A phase based on ultra-pure silica gel (purity > 99 %), metal content < 10 ppm, pH-stability 2 - 8, pore size 300 Å, particle size 3 μm, 5 μm, 10 μm (15 μm, 20 – 45 μm on request).
Hydrophilic and polar biomolecules, peptides, very polar biomolecules separated with 100 % aqueous eluents.
