Compared to conventional HPLC applications using 3 – 5 μm particle sizes, ultra fast separations with superior efficiency are made possible through the use of sub-2 μm and 2 µm particles on UHPLC columns. Advantages of using UHPLC columns are:
- faster analysis (up to 10 times)
- improved resolution
- enhanced sensitivity
- excellent peak shape
- eluent saving
Typical KNAUER UHPLC columns with 2 µm particle size can be found in The Eurospher II family.