The Autosampler
AS 6.1L can inject from up to 768 positions when equipped with microtiter plates (either high or low formats) or from up to 108 standard 1.5 ml sample vials. Sample carryover is significantly minimized thanks to a highly-effective interior and exterior needle wash procedure. This autosampler is also fast and flexible: one complete sample injection cycle takes less than one minute, including needle wash. Three different injection modes are supported; “full loop filling” (highest precision and reproducibility), “partial loop filling” (variable volumes, e.g. for dilution series) and “µl pickup” (loss-free injection of extremely small sample volumes), allowing the user to optimize sample usage. The headspace pressure function prevents bubbles from forming in the vial during sample uptake. Precolumn derivatization is supported. Preparative version for sample volumes up to 10 ml with sample tray cooling (4 - 40°C).
The accessory kit includes a vial plate for 30x 10 ml vials (A500507).
Precise injection with Autosampler AZURA AS 6.1L
Front view of Autosampler AZURA AS 6.1L
An example HPLC system containing the AZURA AS 6.1L
High precision injection
Low carry-over due to efficient needle wash
Supports three injection modes: full loop, partial loop filling, and µl pickup
Headspace pressure function prevents bubbles at sample uptake
| Autosampler Flow Path | Preparative |
|---|---|
| Maximum back pressure | 350 bar |
| Vial/plate dimensions | well plate dimensions according to ANSI SLAS 4-2004 (formerly ANSI/SBS 4-2004) max. plate/vial height: 47 mm (incl. septa or capmat) |
| Injection volume range | 1 µl–10 ml depending on sample loop |
| Sample loop | 10 ml |
| Dispenser syringe | 2500 µl |
| Headspace pressure | built-in compressor, only for sample vials with septum |
| Switching time inj. valve | < 100 ms |
| Piercing needle precision | ± 0.6 mm |
| Sample tray cooling | 4–40 °C |
| Vial detection | missing vial/well plate detection by sensor |
| Wetted materials | ETFE (buffer & needle tubing), stainless steel (sample needle, valve stator), PEEK (rotor seal), Kel-F (syringe valve), glass (syringe), PTFE (tip of syringe plunger) |
| Injection modes | partial loop filling |
|---|---|
| Injection precision | RSD (Rel. Standard Deviation): full loop injection: < 0.3 %, partial loop injection at volumes > 5 µl: < 0.5 %, microliter pickup injection at volumes > 5 µl: < 1.0 % |
| Sample carryover | < 0.1 % with standard needle wash |
| Injections per vial | max. 9 injections |
| Injection cycle time | minimum 7 s from the same vial, 14 s from different vials;< 60 s for>100 µl sample injection in all injection modes, incl. 300 µl needle wash |
| Analysis time | max. 9 h, 59 min, 59 s |
| Inputs | 2 programmable TTL inputs (next injection, freeze, stop) |
|---|---|
| Outputs | 1 programmable relay output (inject marker, auxiliary, alarm) |
| Control | Ethernet (LAN) |
| Interfaces | LAN, analog |
| Ambient conditions | temperature range: 10–40 °C; 50–104 °F air humidity: 20–80% |
|---|
| Power supply | 95–240 V AC |
|---|---|
| Dimensions | 364 x 379 x 623 mm (W x H x D) |
| Weight | 32 kg |
Accessory kit for autosampler with vials, caps, septum and pliers for opening and closing
Article No.: A0664
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Maintenance kit for Autosampler AS6.1L, S3950 (preparative) - including all wear parts: sample needle, air needle, rotor seal, syringe, syringe valve, buffer tubing, wash position
Article No.: ARA14
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AZURA® Autosampler AS 6.1L analytical HPLC autosampler, 1240 bar, with sample cooling/heating
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AZURA® Autosampler AS 6.1L analytical HPLC autosampler, 345 bar, with biocompatible flow path
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AZURA® Autosampler AS 6.1L analytical HPLC autosampler, 345 bar, with biocompatible flow path and sample cooling/heating
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AZURA® Autosampler AS 6.1L preparative HPLC autosampler, 350 bar, with biocompatible flow path and sample cooling/heating
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AZURA® Autosampler AS 6.1L preparative HPLC autosampler, 350 bar
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