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Analysis of Bisphosphonate Pamidronate Disodium by precolumn derivatization and fluorescence detection

Application No.: VPH0024J

Analysis of Bisphosphonate Pamidronate Disodium by precolumn derivatization and fluorescence detection

Eurospher C18 packing material can be universally used in different application areas and has been on the market for more than 15 years. The most often used material is the endcapped Eurospher 100 C18 for the reversed phase mode. The C18 phase can be considered for the determination of water soluble vitamins, steroids, catecholamines, sedatives and in many other application fields in the analytical as well as preparative range. The stationary phase is stable in a pH range of 2 - 8.5. Eurospher C18 is the workhorse for reversed phase applications.

Technical Data

Application

Method HPLC

Separation conditions

Mode RP
Substances Pamidronate disodium, Disodium 3-amino-1-hydroxypropylidenebisphosphonate pentahydrate (IS)
Key words Drugs, Bisphosphonate
CAS number 40391-99-9, 109552-15-0

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