What does "UHPLC" mean?

Q: What does "UHPLC" mean?

UHPLC is the short term for U ltra H igh P erformance L iquid C hromatography. It is a variant of HPLC using columns with particle sizes ≤ 2 µm, which realizes very short column length to shorten the analysis time. Typical UHPLC pumps can work up to 1000 bar and the whole UHPLC system is dead volume optimized (&sim;150 µl) to avoid peak broadening and get the highest efficiency.

UHPLC is the short term for Ultra High Performance Liquid Chromatography. It is a variant of HPLC using columns with particle sizes ≤ 2 µm, which realizes very short column length to shorten the analysis time. Typical UHPLC pumps can work up to 1000 bar and the whole UHPLC system is dead volume optimized (∼150 µl) to avoid peak broadening and get the highest efficiency.