Determination of retention behavior of cannabis extract by column screening

The need of high purity cannabinoids is continuously growing. For this reason, it is of fundamental importance to find high selective and efficient methods for their purification. In this application, the separation of six cannabinoids contained in a crude CBD extract has been evaluated on six analytical columns with four different mobile phase compositions under normal phase conditions. The information obtained could be useful for the set-up of following purification steps.

Methode	HPLC
Modus	RP, NP
Substanzen	CBD, CBDA, CBG, CBN, Δ9–THC, THCA, CBC, CBL
Schlüsselwörter	Purification, cannabidiol, CBD, analytical columns
Version	Version 1 I 02/2021