Webinar: Purification and Quality Control of Oligonucleotides
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Webinar: Purification and Quality Control of Oligonucleotides
Join us for this Webinar together with YMC
Oligonucleotides are very important biopharmaceuticals with a rapidly growing importance. However, due to the high similarity of impurities resulting from synthesis, purification can be challenging.This seminar demonstrates a successful large-scale purification of an oligonucleotide using anion exchange chromatography (AEX) as well as efficient quality control using ion pairing reversed phase chromatography (IP-RP).
Content and Learning Objectives:
- How to perform a large-scale AEX purification: Design of a preparative system and useful features
- Advantages and limitations of using AEX for preparative purification
- What to consider when developing an IP-RP method: Selection of stationary phase, ion-pair reagent, and solvent conditions
- How to improve analytical results by using bioinert column hardware
Speakers:
Dr. Ulrike Krop, KNAUER Wissenschaftliche Geräte GmbH
Dr. Daniel Eßer, YMC Europe GmbH