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AZURA Hybrid Analytical/Preparative System - system layout

2-in-1 system: Hybrid analytical/ preparative HPLC system for optimized methods

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Article No.: A48025
Articlename: AZURA Hybrid Analytical/ Preparative system

2-in-1 system: Hybrid analytical/ preparative HPLC system for optimized methods


Combine preparative and analytical runs in one HPLC system

When separating and purifying molecules by liquid chromatography (LC), it is necessary to develop the method with a preparative high-performance liquid chromatography (HPLC) system. The purification process is often verified for quality and quantity of the products by analytical HPLC. In this case two LC systems, an analytical and a preparative, are needed for a purification process and the following analysis. The AZURA Hybrid Analytical/Preparative system is a combination of these two systems. The system is capable of isolating a single substance from a mixture and afterwards perform an automated purity analysis. For proof of concept caffeine was purified from paracetamol and analysed within the same system. A tech note describes in detail the system set up and the different method steps.

Technical Data

System specification

System type Lab
Max. flow rate 50 ml/min
Gradient hpg
Maximum delivery pressure [psi] 4350 psi
Maximum delivery pressure [bar] 300 bar
Maximum delivery pressure [MPa] 30 MPa
Detector Variable single wavelength detection UV/VIS
Injection automatic injection
Fractionation multi-position valve
Software ClarityChrom

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