HPLC & UHPLC detectors from MS/MS to UV and beyond ...

KNAUER gives you the opportunity to analyze nearly every compound due to a large portfolio of HPLC detectors and detection principles.

Spectrophotometry of UV & visible light
Refractive index detection (RI), refractrometry
Fluorescence detection, fluorimetry (FL)
Evaporartive light scattering detection (ELSD)
Mass spectrometry (MS)
and more ...

For achieving your analysis goals and for matching your separation scale, our HPLC detectors are flexibly adjustable, including choices of flow cells, fiber optics, and nebulizers. With outstanding sensitivity, stability and usability the HPLC detection systems offered by KNAUER match your everyday challenges. KNAUER HPLC detectors can be integrated into nearly every HPLC system to match your specific requirements and can be operated with a broad range of software packages.

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High-performance LC-MS/MS mass spectrometry solutions

Triple Quad™ 3500 and 4500 MS/MS systems

These SCIEX Triple Quad MS/MS systems provide the productivity, reliability, and robustness required for today’s analytical laboratories for quantitation of hundreds of compounds in hundreds of samples – day after day, year after year.

These MS detection systems allow quantification of acidic, neutral and basic analytes in one shot. The compact SCIEX triple quad design saves you valuable bench-space.

The Triple Quad 3500 offers expert level performance at an entry level price. The Triple Quad 4500 enables even higher sensitivity and performance for the most demanding analytical applications.

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Sensitive UV/VIS detectors

We provide a choice of UV/VIS detectors, ranging from single variable wavelength to 8-channel diode array detector with LightGuide total reflection technology.
The AZURA DAD 6.1L is equipped with revolutionary KNAUER Polka-Dot technology providing maximum light intensity and low noise over the whole UV/VIS spectrum. This technology provides more light than previous shine-through lamp configurations.

Both AZURA diode array detectors DAD 6.1L and DAD 2.1L provide high spectral resolution enabling optimized identification and sample characterization.

Sensitive – LightGuide flow cells and Polka-Dot technology
Accessible – easy lamp and flow cell exchange from the front
Flexible – wide range of flow cell for high application versatility
Robust – intelligent temperature control for minimal drift

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AZURA® UV/VIS Detector	UVD 2.1S	UVD 2.1L	MWD 2.1L	DAD 2.1L	DAD 6.1L
	Compact and versatile UV detector	Reliable UV/VIS detector for a wide spectrum of applications	Robust multichannel UV/VIS detector	Versatility through a wide flow cell range	High-end diode array detector with outstanding performance
Wavelength range (nm)	190–500	190–750	190–700	190–700	190–1000
Channels	1	1	8	8	8
3D data acquisition				+	+
Data acquisition rate^*	50 Hz	50 Hz	100 Hz	100 Hz	100 Hz
Fiber optics available	+	+	+	+	+
LightGuide flow cells			+	+	+
PressureProof flow cells			+	+	+
Biocompatible^** flow cells	+	+	+	+	+

Do you need more information or a quote? We are happy to help you!

^*| sampling rate, ^**| bio-inert

Which flow cell suits your application best?

Standard HPLC
UHPLC
High sensitivity

PressureProof principle

The KNAUER PressureProof flow cells are available for all AZURA UV/VIS detectors in cartridge and classic design. These highly robust and price attractive flow cells feature an increased back pressure stability (up to 300 bar) and extended flow rates range (up to 20 ml/min).

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Fast HPLC - LightGuide principle

The Standard LightGuide Flow Cell Cartridge combines total reflection technology with small cell volume for high throughput and high resolution applications.

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Ultimately sensitive UHPLC

The High Sensitivity LightGuide Flow Cell Cartridge is available for the entire AZURA DAD series. With the lowest dispersion volume on the market and long path length this total refection flow cell is the ultimate choice for demanding trace analysis.

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HPLC with remote UV/VIS detection

KNAUER fiber optics technology offers the possibility to separate the flow cell spatially from the detector via fiber optic cables in a distance up to 10 meters. This enables the measurement of UV/VIS absorption in flow-through mode remotely from the detector.

Fiber optics enable the flow cell to be located very close to the column, minimizing peak broadening.

The UV nano flow cell with fiber optics technology from KNAUER received the Best of Industry award 2017.

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Remote UV/VIS flow cells with fiber optic connectors

Analytical UV Flow Cell

10 mm path length, 10 µl, 1/16", 300 bar, stainless steel, fiber optic connectors, classical KNAUER flow cell

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Nano Flow Cell

3 mm path length, 6 nl, 375 µm OD, 50 µm ID, 300 bar, fused silica, fiber optic connectors

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Preparative UV Flow Cell

2 mm path length, 3/8" TRI-Clamp connections, 80 bar, stainless steel, fiber optic connectors, changeable to 0.5/1.25 mm

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Dynamic
refractive index (RI) detector for LC

Detection of small amounts of dissolved compounds with little or no absorption in the UV/Vis spectral range represents an analytical challenge even today. The differential refractometer is an established work-horse for the cost-effective detection of alcohols, sugars, lipids or polymers in HPLC (high performance liquid chromatography) and GPC (gel permeation chromatography).

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No chromophor? No problem.
MEET the AZURA RI Detector 2.1L

Universal detection

AZURA RID 2.1L displays increased sensitivity and baseline stability, it is a sensitive and competitively priced differential refractometer. It is suitable for detecting compounds with little or no UV activity such as alcohols, sugars, lipids or polymers.
Great performance

The AZURA RID 2.1L is a highly competitive and sensitive refractive index detector, ideal for fast and reliable routine analysis of non-UV absorbing substances. The intelligent temperature control guarantees fast baseline stabilization and stable operation
Great stability

Furthermore, the long-life LED, highly pressure resistant flow cell, improved safety features and enhanced diagnostics functions guarantee easy handling and minimal maintenance.
Great versatility

The wide linear dynamic range and 10 ml/min maximum flow rate make the AZURA RID 2.1L the perfect choice for most laboratory tasks.

refractive index detectors

Highly sensitive refractive index detector for liquid chromatography

AZURA® RID 2.1L analytical refractive index detector with flow cell

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High flow rate compatible RI detector for LC and process technology

AZURA® RID 2.1L high-flow preparative refractive index detector with flow cell and external pressure release valve

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A wide range of third-party lc detectors can be seamlessly integrated into AZURA analytical systems

Gradient compatible universal detection

Using the unique Low Temperature technology, this Evaporative Light Scattering detector 85 LT allows universal high sensitivity analysis.

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ELSD for preparative HPLC

Universal evaporative light-scattering detection for HPLC, with innovative SAGA technology, ideal for preparative applications

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Sensitive and selective fluorophor detection

The fluorescence detector RF-20A provides world-class sensitivity, excellent maintainability and diverse validation / support functions. It supports a wide range of applications from conventional to high-performance analysis

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Conductivity monitor

Biocompatible conductivity monitor Mikron-81 e.g. for fast protein chromatography (FPLC) up to 100 ml/min

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See the complete KNAUER LC Detector portfolio

Detectors

UV/VIS
Refractive index
Fluorescence
Light scattering
Conductivity
Special applications

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Flow cells

Analytical
Semi-preparative
Preparative
FPLC / Bio LC
Fiber optics
Special applications

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Accessories & spare parts

Lamps
Fiber optic cables
Waste tubing kits
Repair kits

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HPLC & UHPLC detectors from MS/MS to UV and beyond ...

High-performance LC-MS/MS mass spectrometry solutions

Triple Quad™ 3500 and 4500 MS/MS systems

Sensitive UV/VIS detectors

Do you need more information or a quote? We are happy to help you!

Which flow cell suits your application best?

PressureProof principle

Fast HPLC - LightGuide principle

Ultimately sensitive UHPLC

HPLC with remote UV/VIS detection

Remote UV/VIS flow cells with fiber optic connectors

Analytical UV Flow Cell

Nano Flow Cell

Preparative UV Flow Cell

Dynamic
refractive index (RI) detector for LC

No chromophor? No problem.
MEET the AZURA RI Detector 2.1L

Universal detection

Great performance

Great stability

Great versatility

refractive index detectors

Highly sensitive refractive index detector for liquid chromatography

High flow rate compatible RI detector for LC and process technology

A wide range of third-party lc detectors can be seamlessly integrated into AZURA analytical systems

Gradient compatible universal detection

ELSD for preparative HPLC

Sensitive and selective fluorophor detection

Conductivity monitor

See the complete KNAUER LC Detector portfolio

Detectors

Flow cells

Accessories & spare parts

More about AZURA HPLC/UHPLC

Do you need more details or a quote?

HPLC & UHPLC detectors from MS/MS to UV and beyond ...

High-performance LC-MS/MS mass spectrometry solutions

Triple Quad™ 3500 and 4500 MS/MS systems

Sensitive UV/VIS detectors

Do you need more information or a quote? We are happy to help you!

PressureProof principle

Fast HPLC - LightGuide principle

Ultimately sensitive UHPLC

HPLC with remote UV/VIS detection

Remote UV/VIS flow cells with fiber optic connectors

Analytical UV Flow Cell

Nano Flow Cell

Preparative UV Flow Cell

Dynamic refractive index (RI) detector for LC

No chromophor? No problem. MEET the AZURA RI Detector 2.1L

Universal detection

Great performance

Great stability

Great versatility

refractive index detectors

Highly sensitive refractive index detector for liquid chromato­graphy

High flow rate compatible RI detector for LC and process technology

A wide range of third-party lc detectors can be seamlessly integrated into AZURA analytical systems

Gradient compatible universal detection

ELSD for preparative HPLC

Sensitive and selective fluorophor detection

Conductivity monitor

See the complete KNAUER LC Detector portfolio

Detectors

Flow cells

Accessories & spare parts

More about AZURA HPLC/UHPLC

Do you need more details or a quote?

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Dynamic
refractive index (RI) detector for LC

No chromophor? No problem.
MEET the AZURA RI Detector 2.1L

Highly sensitive refractive index detector for liquid chromatography